HLA-B45 - HLA-B45


HLA-B (alfa) -β2MG bog'langan peptid bilan
asosiy histokompatiblilik kompleksi (inson), I sinf, B45
Allellar	B * 4501, 4502. .
Tuzilishi (Qarang HLA-B )
Umumiy ma'lumotlar
Lokus	xr.6 6p21.31

HLA-B45 (B45) - bu HLA -B serotip. Serotip HLA-B ning B * 45 gen-allel oqsil mahsulotlarini aniqlaydi.^[1]

B45 - bu split antigen ning keng antigen B12, va singil turi B44.Gene mahsulotlari 45 emas, 44

Serotip

Serotiplarning B45, B12 va B44 tomonidan tan olinishi
HLA B * 44 gen mahsulotlari^[2]
B * 45	B45	B12	B45	Namuna
allel	%	%	%	hajmi (N)
*4501	93	1	1	2307
*4502	75			4
Allellar bilan bog'lanish IMGT /HLA Ma'lumotlar bazasi EBI

Allellar

Italiyalik suyak iligi donorlarida yangi haplotip topilganligi haqida xabar berildi. A2-CW * 1601-B45- DRB1 * 1101-DRB3 * 0301-DQA1 * 0102-DQB1 * 0502. Ushbu haplotip Afrikadan Cw * 1601 va B45 komponentlari hamda DR11-DQ5.2 komponentlari bilan Evropada juda kam uchraydigan ajdodlarimizni ko'rsatmoqda.^[3]

Adabiyotlar

^ Marsh, S. G.; Albert, E.D .; Bodmer, V. F.; Bontrop, R. E.; Dupont, B .; Erlich, H. A .; Fernández-Vína, M.; Geraghty, D. E.; Xoldvort, R .; Xerli, K. K .; Lau, M .; Li, K. V.; Mach, B .; Mayers, M .; Mayr, V. R.; Myuller, C. R .; Parham, P .; Petersdorf, E. V.; Sasazuki, T .; Strominger, J. L .; Svejgaard, A .; Terasaki, P. I .; Terci, J. M.; Trowsdeyl, J. (2010). "HLA tizimi omillari nomenklaturasi, 2010 yil". To'qimalarning antigenlari. 75 (4): 291–455. doi:10.1111 / j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
^ IMGT / HLA dan olingan
^ Daielli C, Salvaneschi L, Gidini G, Ambroselli F, Gatti C, Martinetti M (aprel 1996). "HLA-B45 musbat suyak iligi donorlarida yangi italyan haplotipi ustunlik qiladi: HLA-A2, CW * 1601, B45, DRB1 * 1101, DRB3 * 0301, DQA1 * 0102, DQB1 * 0502". To'qimalarning antigenlari. 47 (4): 341–3. doi:10.1111 / j.1399-0039.1996.tb02564.x. PMID 8773326.

[pmid15787720-1] Marsh, S. G.; Albert, E.D .; Bodmer, V. F.; Bontrop, R. E.; Dupont, B .; Erlich, H. A .; Fernández-Vína, M.; Geraghty, D. E.; Xoldvort, R .; Xerli, K. K .; Lau, M .; Li, K. V.; Mach, B .; Mayers, M .; Mayr, V. R.; Myuller, C. R .; Parham, P .; Petersdorf, E. V.; Sasazuki, T .; Strominger, J. L .; Svejgaard, A .; Terasaki, P. I .; Terci, J. M.; Trowsdeyl, J. (2010). "HLA tizimi omillari nomenklaturasi, 2010 yil". To'qimalarning antigenlari. 75 (4): 291–455. doi:10.1111 / j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.

[2] IMGT / HLA dan olingan

[pmid8773326-3] Daielli C, Salvaneschi L, Gidini G, Ambroselli F, Gatti C, Martinetti M (aprel 1996). "HLA-B45 musbat suyak iligi donorlarida yangi italyan haplotipi ustunlik qiladi: HLA-A2, CW * 1601, B45, DRB1 * 1101, DRB3 * 0301, DQA1 * 0102, DQB1 * 0502". To'qimalarning antigenlari. 47 (4): 341–3. doi:10.1111 / j.1399-0039.1996.tb02564.x. PMID 8773326.

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