Tergov gormonal agentlari ro'yxati - List of investigational hormonal agents

Bu tergov ro'yxati gormonal vositalar, yoki hozirda klinik foydalanish uchun ishlab chiqilayotgan, ammo hali tasdiqlanmagan gormonal vositalar. Qavslar ichida ishlab chiquvchi kod nomlari, sinonimlar va firma nomlari bilan birinchi navbatda kimyoviy / umumiy nomlar keltirilgan.

Androgenika

Estrogeniklar

Progestogenik moddalar

Glyukokortikoidlar

Mineralokortikoidika

GnRH / gonadotropinlar

Aralashgan

Shuningdek qarang

Adabiyotlar

  1. ^ a b http://www.evestra.com/index-Dateien/Page1242.htm
  2. ^ a b Ahmed G, Elger V, Meece F, Nair HB, Shnayder B, Vyrva R, Niksis K (oktyabr 2017). "Og'iz orqali so'rilishini yaxshilash va jigarning o'zaro ta'sirini kamaytirish uchun mo'ljallangan preparatning dizayni". Bioorg. Med. Kimyoviy. 25 (20): 5569–5575. doi:10.1016 / j.bmc.2017.08.027. PMID  28886996.
  3. ^ Tong, Youzhi; Chen, Chunyun; Vu, Xuan; Yang, Tsziantao; Chjan, Xuyxui; Vu, Syaojun; Duan, Yanmey; Gao, Vey; Tsian, Veydun; Niu, Xiaoxia; Mi, Lili; Guo, Chuangsin (2014). "Abstrakt 614: Proksalutamid (GT0918), kuchli androgen retseptorlari yo'lining inhibitori". Saraton kasalligini o'rganish. 74 (19 qo'shimcha): 614. doi:10.1158 / 1538-7445.AM2014-614. ISSN  0008-5472.
  4. ^ Elger V, Vyrva R, Ahmed G, Mees F, Nair HB, Santhamma B, Killin Z, Shnayder B, Meister R, Shubert H, Nikisk K (2017 yil yanvar). "Ostrogenni samarali davolash uchun estradiol prodruglari (RaI) va estrogen modulyatsiyalangan jigar funktsiyalariga ta'siri bekor qilindi". J. Steroid biokimyosi. Mol. Biol. 165 (Pt B): 305-311. doi:10.1016 / j.jsbmb.2016.07.008. PMID  27449818.
  5. ^ Liu J, Zheng S, Akerstrom VL, Yuan C, Ma Y, Zhong Q, Zhang C, Zhang Q, Guo S, Ma P, Skripnikova EV, Bratton MR, Pannuti A, Miele L, Wiese TE, Vang G (2016) . "Fulvestrant-3 boron kislotasi (ZB716): biologik mavjud bo'lgan tanlangan estrogen retseptorlari regulyatori (SERD)". J. Med. Kimyoviy. 59 (17): 8134–40. doi:10.1021 / acs.jmedchem.6b00753. PMC  5499704. PMID  27529700.
  6. ^ Vang, G; Liu, J; Chheng, S; Miele, L; Vies, T; Zhong, Q; Guo, S (2017). "Abstrakt P2-08-11: Og'iz orqali biologik mavjud bo'lgan selektiv estrogen retseptorlari regulyatori". Saraton kasalligini o'rganish. 77 (4 qo'shimcha): P2-08-11-P2-08-11. doi:10.1158 / 1538-7445.SABCS16-P2-08-11. ISSN  0008-5472.
  7. ^ https://adisinsight.springer.com/drugs/800038483
  8. ^ https://www.endocrine.org/news-room/2019/endo-2019---second-potential-male-birth-control-pill-passes-human-safety-tests
  9. ^ https://www.endocrine.org/news-room/2018/dimethandrolone-undecanoate-shows-promise-as-a-male-birth-control-pill
  10. ^ https://www.myovant.com/our-science/relugolix/
  11. ^ https://investors.myovant.com/news-releases/news-release-details/myovant-science-announces-97-response-rate-positive-phase-3

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