Rentiapril - Rentiapril

Rentiapril
Ismlar


IUPAC nomi (2R,4R) -2- (2-gidroksifenil) -3- (3-sulfanilpropanoil) -1,3-tiazolidin-4-karboksilik kislota
Identifikatorlar
CAS raqami	72679-47-1^Y
3D model (JSmol )	Interaktiv rasm
ChemSpider	64376^N
PubChem CID	71244
UNII	D0TAM1017B^Y
CompTox boshqaruv paneli (EPA)	DTXSID80230646
InChI InChI = 1S / C13H15NO4S2 / c15-10-4-2-1-3-8 (10) 12-14 (11 (16) 5-6-19) 9 (7-20-12) 13 (17) 18 / h1-4,9,12,15,19H, 5-7H2, (H, 17,18) / t9-, 12 + / m0 / s1^N Kalit: BSHDUMDXSRLRBI-JOYOIKCWSA-N^N InChI = 1 / C13H15NO4S2 / c15-10-4-2-1-3-8 (10) 12-14 (11 (16) 5-6-19) 9 (7-20-12) 13 (17) 18 / h1-4,9,12,15,19H, 5-7H2, (H, 17,18) / t9-, 12 + / m0 / s1 Kalit: BSHDUMDXSRLRBI-JOYOIKCWBM
Jilmayganlar C1 [C @ H] (N ([C @ H] (S1) C2 = CC = CC = C2O) C (= O) CCS) C (= O) O
Xususiyatlari
Kimyoviy formulalar	C₁₃H₁₅NO₄S₂
Molyar massa	313.39 g · mol⁻¹
Boshqacha ko'rsatilmagan hollar bundan mustasno, ulardagi materiallar uchun ma'lumotlar berilgan standart holat (25 ° C [77 ° F], 100 kPa da).
N tasdiqlang (nima bu ^YN ?)
Infobox ma'lumotnomalari

Rentiapril bu ACE inhibitori.^[1]

Adabiyotlar

^ Takase K, Ikuse T, Aono H, Okahara A (yanvar 1995). "Sichqonlardagi angiotenzinni konvertatsiya qiluvchi ferment inhibitori rentiaprilning toksikligini o'rganish". Arzneimittelforschung. 45 (1): 15–8. PMID 7893262.

Gipertenziv dorilar bo'yicha harakat qilish renin-angiotensin tizimi (C09 )
ACE inhibitörleri ("-pril")	Sulfhidril o'z ichiga oladi: Captopril Rentiapril Zofenopril Dikarboksilat o'z ichiga oladi: Enalapril^# Benazepril Silazapril Delapril Imidapril Lisinopril (+ HCT ) Moeksipril Perindopril (+ indapamid ) Quinapril (+ HCT ) Ramipril Spirapril Temokapril Trandolapril Fosfonat o'z ichiga oladi: Ceronapril Fosinopril (+ HCT ) Boshqa / guruhlanmagan: Alatsepril
AIIRAlar ("-sartan")	Azilsartan Kandesartan Eprosartan Fimasartan Irbesartan (+ HCT ) Losartan (+ HCT ) Olmesartan (+ amlodipin, + amlodipin va HCT ) Tasosartan^§ Telmisartan (+ amlodipin, + HCT ) Valsartan (+ amlodipin, + HCT )
Renin inhibitörleri ("-kiren")	Aliskiren (+ amlodipin, + HCT, + amlodipin va HCT ) Remikiren^§
Ikki tomonlama ACE /NEP inhibitörler	Gemopatrilat Ilepatril Omapatrilat Sampatrilat
Neprilysin inhibitörler	Sakubitril (+ valsartan )
^#JSST-EM ^‡Olingan bozordan Klinik sinovlar: ^†III bosqich ^§Hech qachon III bosqichga

Anjiyotensin retseptorlari modulyatorlar
ATR	Agonistlar: Angiotensin II Angiotensin III Angiotensin IV L-163,491 Saralasin Antagonistlar: Abitesartan Azilsartan Kandesartan Elisartan Embusartan Eprosartan EXP-3174 Fimasartan Forasartan Irbesartan Losartan Milfasartan Olmesartan Olodanrigan PD123319 Pomisartan Pratosartan Ripisartan Saprisartan Sparsentan Tasosartan Telmisartan Valsartan Zolasartan ACE inhibitörler: Alatsepril Benazepril Captopril Silazapril Delapril Enalapril Enalaprilat Fosinopril Gemopatrilat Imidapril Lisinopril Moeksipril Omapatrilat Perindopril Quinapril Kinaprilat Ramipril Rentiapril Rescinnamine Spirapril Spiraprilat Temokapril Trandolapril Zofenopril Zofenoprilat Renin inhibitörleri: Aliskiren Ciprokiren Ditekiren Enalkiren Imarikiren Pepstatin Remikiren Terlakiren Zankiren Propeptidlar: Anjiyotensinogen Angiotensin I
Kombinatsiyalar:	Amlodipin / valsartan Olmesartan / amlodipin Olmesartan / amlodipin / gidroxlorotiyazid Valsartan / gidroxlorotiyazid Valsartan / gidroxlorotiyazid / amlodipin
Shuningdek qarang Retseptor / signalizatsiya modulyatorlari Signal peptid / oqsil retseptorlari modulyatorlari

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